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Break free from eczema with Crypto PPARs.

Eczema is caused by underlying inflammation. The development of this inflammatory skin condition involves substances that create adverse immune reactions. These include various allergens as well as hereditary and environmental factors. 

Many people with eczema use plenty of products, practices, and medicines to help manage their symptoms. Before you consider any treatment, it's essential to understand what triggers your eczema. Learning about the irritants in your everyday surroundings can help you better manage the condition whether you use traditional medications, alternative therapies, or both. 

Before that, get to know the root cause of eczema. The root cause of eczema is thought to be associated with immune function and immune disorders. Hence, "treating" the immune system, ensuring the immune system's proper role is another crucial concern to cure eczema. People with eczema tend to have an over-reactive immune system. When triggered by a substance inside or outside the body, the immune system responds by producing inflammation. This inflammatory response causes itchy, painful, rash-like symptoms common to several types of eczema.

Hence, treating the immune system, ensuring its function is another crucial concern to heal eczema. In this case, PPARs supplement plays a pivotal role in healing the immune system naturally and improving immune system disorders.

Anti-inflammatory properties of PPARs help promote the healing of rashes, reduce the flare-up frequency, and further speed up the recovery process of eczema. By decreasing the inflammatory hormones, PPARs do not only reduce the inflammation but also reduces the pain. It also prevents the production of a pro-inflammatory response, minimizing the possibilities of relapse after recovery. 

PPARs function in skin repair and wound healing.

The Peroxisome Proliferator-Activated Receptors (PPARs) alpha, beta, and gamma are ligand-activated transcription factors belonging to the nuclear receptor superfamily. Besides their regulatory role on lipid and glucose metabolism, they exert anti-inflammatory properties. In the skin, both PPAR-alpha and PPAR-beta regulate keratinocyte proliferation/differentiation and contribute to wound healing. The 3 PPARs isoforms are expressed by several cell types recruited into the dermis during inflammation.

 

Activation of PPARs will enhance immunity cell proliferator capability, which in other words, PPARs will boost our immunity. PPAR α and PPAR β may also play a role in human keratinocyte differentiation. PPARs are involved in diverse biological activities in the epidermis, such as keratinocyte proliferation/differentiation, epidermal barrier recovery, sebocyte activity, and melanocyte differentiation. Besides, their overall anti-inflammatory functions are well characterized. 

PPARs α – are also involved in skin homeostasis. PPAR-alpha controls keratinocyte proliferation, contributes to wound healing, and regulates skin inflammation. PPAR-alpha activation exerts anti-inflammatory effects in various skin conditions, such as irritant, allergic contact dermatitis, atopic dermatitis, and UV-induced erythema. 

PPAR β - represent an attractive pharmaceutical target due to its essential functions as a regulator of cell survival, proliferation, and migration, and in the repair process in general. Regulates sebocyte differentiation, promotes hair follicle growth, and has pro-differentiating effects in keratinocytes in normal and inflammatory conditions. It is induced (among other factors) by TNF α, stimulates proliferation and block apoptosis in keratinocytes, and induces angiogenesis. 

PPAR γ – keratinocyte differentiation, permeability barrier recovery, dermal wound closure, sebaceous gland formation, sebocyte differentiation, and melanogenesis. 

PPARs as an effective immune booster. 

Activation of PPARs will enhance immunity cell proliferator capability, meaning PPARs will boost our immunity. PPARs are effective in inducing an immune profile similar to the dominance of Th2 Cells. PPAR gamma and its ligands are the most critical ones for modulating immune cells like monocytes, T cells, and N.K. Cells, and inflammatory reactions. 

PPAR also plays a critical role in activating the cells' functions and increasing cell respondents by fueling the immune cells to function correctly. Deciphering the mechanism of action of PPAR-gamma and its ligands may lead to a new therapeutic regimen for treating diseases involving dysfunction of the immune system. Furthermore, PPARs have also been recognized as contributing significantly to the immune response through their ability to avoid the expression of inflammatory cytokines and direct various immune cells toward anti-inflammatory phenotypes, making PPARs effective in inhibiting inflammatory mediators. In short, the anti-inflammatory and immunity-boosting characteristics of PPARs have made PPARs a highly effective supplement in the treatment of eczema.

Besides the immune system, one of the most effective benefits of PPARs is that PPARs contain a high concentration of Cell Growth Factor (C.G.F.). The cell growth factor is a naturally occurring substance in crypto PPARs capable of stimulating cellular growth and cell rejuvenation. This further helps the healing process of damaged body tissues, allowing cells to repair faster and effectively. Thus, it's an essential role of C G F in helping skin to recover without scars. 

PPARs is one of the most effective supplements as an immunity booster in terms of the immune system. Activation of PPARs will enhance immunity cell proliferator capability and therefore boost the immune system. In terms of recovery, PPARs contain a high concentration of Cell Growth Factor (C.G.F.). C.G.F. is a naturally occurring substance capable of stimulating cellular growth and healing of cells. It supports the healing process of damaged body tissues, allowing the cells to repair faster and more effectively. It is highly beneficial in helping the dry, cracked skin to heal naturally and quickly.

Moreover, despite taking Crypto PPARs, it is also essential to maintain a healthy and balanced diet. Focus on contemplating foods rich in anti-inflammatory properties includes fish, turmeric, and cinnamon, which reduces flare-ups. Avoid foods high in allergens, such as peanuts, dairy eggs, and dairy products, which are ubiquitous inflammatory foods.

It is also essential to focus on products to be applied to our body and use clothes that do not cause aggressive reactions and irritations to the skin. Stress is a common eczema trigger too. Hence, effective stress management is essential again. You may try out meditations, tai chi, and yoga. 

 

Crypto PPARs are the far most effective supplements as an immunity booster.

Activation of PPARs will enhance immunity cell proliferator capability and boost the immune system. Moreover, the PPARs content also aid skin healing, tissue rejuvenation, and cell to repair faster and more effectively. It's highly beneficial for damaged and wounded skin to heal faster, naturally, and quickly. 

Surviving eczema days

Surviving eczema days

Eczema is a skin condition where the skin patches become itchy, cracks, inflamed, and rough. At times eczema can even cause blisters. Those suffering from severe eczema will often find flakey patches of red and irritated skin. Over time, the condition also results in your skin becoming weaker, thinner, and more fragile.

Atopic dermatitis is the most common type of eczema and is believed to be caused by immune dysregulation and environmental factors. Environmental factors include smoke, pollen, soaps, and fragrances may worsen eczema condition. Certain foods, such as nuts and dairy, can also trigger the symptoms of eczema. Eczema not contagious. Some people may outgrow the condition, whereas some people continue to have it throughout adulthood.

There are 7 different eczema types; atopic dermatitis, contact dermatitis, dyshidrotic eczema, nummular eczema, seborrheic eczema, and stasis dermatitis. Dermatitis refers to skin inflammation. People with eczema often have allergies or asthma, along with itchy, red skin. Eczema comes in a few other forms too. Each eczema type has its symptoms and triggers.

SYMPTOMS:

  1. Dry, scaly skin
  2. Redness
  3. Itching, sometimes intense
  4. Small, raised bumps
  5. Thickened, cracked, and scaly skin 
  6. Swollen skin, sensitive skin

CAUSES

Healthy skin helps us to retain moisture and protects us from bacteria, irritants, and allergens. Eczema is related to a gene variation that affects our skin's ability to provide this protection. This condition causes our skin to be affected by environmental factors, irritants, and allergens. In some children, food allergies may play a role in causing eczema.

COMPLICATIONS

The complication of eczema may include:

  1. Asthma and Hay fever -Eczema sometimes precedes the conditions. More than half of young children with atopic dermatitis develop asthma and hay fever by 13 years old.
  2. Chronic, itchy, scaly skin - Eczema causes skin inflammation, which often starts with a patch of itchy skin, eventually lead to the itch-scatch cycle. 
  3. Skin infections – Repeated scratching can break the skin, which causes open sores and cracks. These sores and cracks increase the risk of infection from bacteria and viruses. 
  4. Irritant hand dermatitis – Irritant hand dermatitis is a form of contact dermatitis. The skin is injured by environmental factors such as cold, over-exposure to water, or chemicals such as acids, alkalis, detergents, and solvents. 
  5. Allergic contact dermatitis – This condition is common in people with atopic dermatitis.
  6. Sleep problems - The itch-scratch cycle can cause poor sleep quality. 

Treatment and management 

The primary goal of eczema management is to improve life quality to ensure we participate in our school, work, social, and family activities. People with eczema often face social withdrawal issues or are socially stigmatized by others. Besides, sleep should be restful and undisturbed by the need to scratch the skin. 

Managing itch

Chronic itchy skin is a universal symptom of most types of eczema. Eczema itch is usually diff from irritation from a bug bite/poison ivy. A common medication used for the itch, such as anti-histamines, does not work well with eczema itch. For many people, chronic irritation from eczema just likely to involve physically. People with chronic itch are more likely to experience poor sleep and mental health issues such as depression and anxiety.

Treating itchy skin 

The most critical step in manage itchy skin is to reduce the risk of its happening in the first place. This can be done by moisturizing routine, clean and regular bathing, and using the prescription medication as prescribed without skipping. Medical experts recommend applying moisturizers liberally throughout the day to replenish the skin barrier.

Natural remedies for itch include soaking in the bath with oatmeal and baking soda. This can also be made into a paste and applied directly to the skin. Topical and immunosuppressant medications also reduce the symptoms of itch. In some cases, health care providers prescribe antidepressant medications such as mirtazapine, which effectively relieves irritation at night. Pramoxine, an anesthetic, or certain antibiotics is used for skin infections. Medical experts often advise not to scratch too much because it can lead to more rashes, inflamed and thickened skin, which may cause infections if the surface of the skin is broken.

Avoid possible trigger

One of the best eczema management is to avoid possible triggers of eczema. Getting to know the possible triggers and manage the flare-up is one of the best things we can do.

Irritants: Irritants such as chemicals, fragrances, certain fabrics, detergents, and smoke can further irritate eczema patients' skin. 

These are few steps to follow to reduce irritant exposure:

  1. Wash new clothes before wearing them.
  2. Keep fingernails short and smooth to prevent scratching scars and injury damage.  
  3. Wear comfortable clothing. Choose the right fabrics. People with eczema find that wool and synthetic materials, such as nylon and polyester, cause sweating, irritation, and overheating, leading to severe itchiness.  
  4. If you go swimming, bathe immediately afterward to avoid exposure to chemicals found in swimming pools and beaches.
  5. Use broad-spectrum ultraviolet (UV) protective sunscreen (UV-A & UV-B) with 15 or more SPF. 

Tips for itch relief

  1. Get to know your triggers and avoid your itch triggering.
  2. Apply cold cleansers.
  3. Use clear, soft, and breathable clothing.
  4. Use skin cleansers with lower PH.
  5. Pat the itchy skin or try to pinch. Avoid scratching as possible.
  6. Perform wet wrap therapy.
  7. Do cold compress with diluted apple cider vinegar.
  8. Moisturize frequently throughout the day with an ointment or cream that contains ceramides.

How commercial soap fooled us

How commercial soap fooled us

Commercial soap is the mass-produced soaps by large multinational companies. It is a factory or machine made by large batches with harsh chemicals, synthetic ingredients, cheap fragrance oils, and artificial colors, all of which can irritate and dry out your skin. Today, there are very few true/pure soaps on the market. Most body cleansers, soap, shower gels, either liquid and solid, are synthetic detergent products. If you take a closer look at commercials soaps sold in stores, likely you won't _and the term "soap" on the packages. Companies cannot use the word soap unless it is truly a REAL handcrafted bar of soap. On the other hand, they are labeled as "beauty bars," "dry skin cleaners," and "moisturizing bars."

 

The ingredients in some commercials bars on the market make them ineligible to be called and advertised as soap. The word "soap" has a legal de­nition provided by FDA. Most commercials brands are not called soap because they are actually "detergents" by ingredients and do not meet the legal de­nition of soap.

It is also essential to be educated about harmful ingredients before purchasing soap products. You want to refresh and moisturize your skin, not to pollute it with chemicals. Don't you? If you can't pronounce the words back of the soap labels- put the product down!

 

Here is a shortlist of common harmful ingredients of commercials soaps;

  1. PARABENS - It is a type of chemical preservatives and is considered a harmful ingredient. Found in the majority of cosmetics and beauty products.
  1. PHTHALATES - known to cause cancer. It is a substance used to manufacture plastics. Commonly used to create fragrances and added to cosmetics to extend shelf life.
  1. SYNTHETIC PERFUME - Artificial perfume scents smell nice, yet they are linked to allergies and hormone issues. They are likely to cause skin conditions and aggravate existing problems such as acne. 
  1. SODIUM LAURYL SULFATE (SLS) - SLS is a surfactant or detergent found in many personal care products such as soaps, shampoos, toothpaste, etc. It is used as a foaming agent for its cleaning and emulsifying properties. They behave similarly to soap. Like other detergents, SLS is an irritant that can cause skin irritation and dry skin.
  1. TRICLOSAN - Can you believe this ingredient is a pesticide? Yes, its antibacterial and antifungal properties make it an attractive option for soap companies, but not for your health. Triclosan can irritate the skin, eyes, and lungs and can also disrupt your hormones. 

Every big company and skincare manufacturers have their deep secrets on the ingredients used for its products.

For example, the FDA doesn't require disclosing the ingredients in a company's trademark "fragrance "on its label. That means whichever ingredient added to the soap under the category of "Fragrance" does not need to be disclosed. Thus, the scented soap could contain harmful chemicals without the buyer knowing. Some of these chemicals concoctions are skin irritants and carcinogenic.

 

Glycerin is a naturally occurring component that attracts water to the skin, which effectively balances our skin's moisture level. Glycerin is also known to prevent signs of aging by helping skin cells to mature properly. When skin cells don't mature properly, they become hyper-proliferative, leading to skin conditions as hives, rashes, allergies, and atopic dermatitis. Studies show that the introduction of glycerin to your skincare regimen can provide a protective barrier and train your skin cells to cycle through their lifespan productively.

 

Typically factory-made soaps have all of the glycerin removed and placed into different additional products such as lotions and creams. Thus, their soaps lack glycerin. The reason is that instead of buying one product that will clean and moisturize, a consumer now has to buy two products to serve the same purpose. Sneaky! The main hack behind these synthetic, dry ingredients and removing glycerin is to save money from their bottom line and not offer us quality skincare! In glycerin replacement, commercial companies often use synthetic chemicals that strip all of its oils' skin and act as skin irritants. These are why bar soaps are often categorized as detergents, washes, or cleansers rather than soap. With handcrafted soaps, glycerin remains in the soap. The result is mild, pure soap that gently cleanses your skin without being harsh, irritating, or drying.

 

Today, there is an increased awareness of the possible effects of many synthetic ingredients and additives in commercial soaps. Consumers have been educated regularly, and they are opting for natural products. Even large companies are starting to advertise "natural ingredients' in their products. Beware! The addition of one or two natural ingredients does not make the product "all-natural."