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A little Q&A on Crypto PPARs

A little Q&A on Crypto PPARs

HOW DO I KNOW WHICH IS THE RIGHT PRODUCT FOR ME? 

If you wonder which is the right product for you, do not worry. You can always refer to this article. 

1. I am looking for regular supplementation. Which is the right product for me? 

If you're looking for something you can take as regular supplementation purposes, you can always opt for Crypto PPARs 1000 tablets. Crypto PPARs 1000 tablets contain 100% Chlorella Sorokiniana (W87-10). It is our best selling product. It is in tablets, which are convenient and easier to consume compared to other forms of products. We do recommend chewing the tablets instead of swallowing them. 

The tablet is unique as it is rich in vitamins, minerals, and Peroxisome Proliferated Activated Receptors (PPARs), which play a pivotal role in regulating our DNA or Transcriptional Genetic Factors.

Crypto PPARs contains more than 96 nutrients, trace minerals, amino acids, an extensive array of vitamins, and much more in a bottle that makes it a "One-For-All" solution to all individual's lifestyles. Its efficacy is prominent, and one could experience the positive effect of the product within 45 minutes!

It is 100% bio-organic algae with the complete profiles of all vitamins and minerals that human needs and having the full spectrum of Bio-PPARs Profile that contains all Alpha, Beta and Gamma agonist

Crypto PPARs: 

  • Capable of lowering triglyceride in the blood
  • Capable of lowering low-density lipoprotein – cholesterol
  • Capable of improve immunity

DOSAGE: We always recommended taking 15 tablets for the adult category- 2 to 3 times per day. For children's dosage, do refer to us. 

2. What if I have a critical illness. How do I know which product is the right one for me?

As for critical illnesses such as cancer, we recommend going for Crypto PPARs Extract Liquid as it contains 100% PPARs. Crypto Liquid Extracts Plus is the most potent of all Crypto PPARs range of products because of the unique cultivation and process behind the making of the proprietary product. You can feel the difference within 30 to 45 minutes upon the consumption of the product. 

DOSAGE: 1 to 2 liquid vials depending on the health condition. Some illnesses and conditions may require the intake of both tablets and liquid. Do refer us for the dosage. 

3. Can I consume Crypto PPARs Softgel Capsule instead of Crypto PPARs Extract Liquid? 

We receive these questions a lot; thus, we thought of clarifying the differences between these two products. Crypto PPARs Softgel Capsule is not the same as Crypto PPARs Extract Liquid. Some prefer taking soft gel capsules as the price is much lower than liquid, but it does not benefit the same way. 

Crypto PPARs Softgel Capsule is usually recommended for women who have infertility issues or are trying to conceive. It contains wheat germ oil and α-linolenic acid, which is essential for pregnancy. 

 

DOSAGE: 2 to 3 capsules per day depending on the condition.

 

4. What if I feel Crypto PPARs Extract Liquid is very expensive and out of my budget. Can I go for an alternative product?  

We will always recommend the product and dosage according to the illness and health condition of a person. As some might feel the liquid is slightly out of the budget, they can opt for Crypto PPARs Extract Capsule. The difference is that Crypto PPARs Extract Liquid is in active and living form, and the powder is passive and dried. Crypto PPARs Extract Capsule undergoes a spray drying process to preserve its active bio-ingredients. They carry the same essential components like DNA, RNA, Nucleotide, S-Peptide, Peptide, CGF & PPARs. The potency, effectiveness, and absorption rate are slightly slower than liquid extract since they are in dried form. Yet, it still benefits far less than the same as Crypto PPARs Extract Liquid. 

 

5. What if I can't accept the smell of algae?

Over the years, our research team in Taiwan has researched and developed a solution for this issue. Our new formula is more to nutty flavor and a lesser fishy smell. Yet, since the base ingredient is algae, we cannot altogether remove the fishy smell. Thus, our advice for those who can not accept the fishy smell is to swallow the tablet with water instead of chewing the tablets. 

6. Can someone who is undergoing chemotherapy consume Crypto PPARs? 

Yes, you can definitely consume our product even if you are under medication or undergoing chemotheraphy. 

7. Can I mix the intake of Crypto PPARs with other products as well, as in traditional medicine or other supplements? 

We do not encourage to mix the intake of Crypto PPARs with other traditional medicine. The mixture of more supplements/traditional medicine may interrupt with the effectiveness of Crypto PPARs. 

We will come with more common Q&A to assist our customers. If there are any further inquiries or information needed, do not hesitate to contact us. 

PPARs and Lupus

PPARs and Lupus
  • Managing lupus
  • Diet for lupus
  • PPARs and Lupus

 

As mentioned, lupus is a complex autoimmune condition with a wide variety of symptoms. As an autoimmune disease, it can affect any part of the body, including tissues and organs. The only best way is to manage lupus and also prevent the flare from occurring. Lupus management and some lifestyle measure can improve a person's quality of life. 

There are no measures to prevent lupus but knowing the triggers that cause flare can help the person with the condition better to be well prepared when they occur.

Get to know lupus flare: https://crypto.com.my/blogs/news/the-disease-of-1000-faces-lupus.

How can I tell if a lupus flare is coming?

Lupus flare most often has some signs and symptoms. We can always prevent the flares or make them less severe if you spot warning signs and seek treatment immediately. These are some symptoms you might get before the flares, such as:

  • Rash
  • Fever
  • Stomach ache
  • Tired
  • Severe dizziness
  • Headache

There is no way to know if a flare will be mild or severe. Mild or moderate flares may cause only a rash or more joint pain. But severe flares can damage organs in the body, including fluid buildup around your heart and kidney disease.

Should I watch over my diet because I have lupus?

Diet and lupus can also be related. There is no specific food to be eaten or to be avoided. Yet, knowing the right food can prevent the triggers or flare. In general, eating a nutritious, well-balanced, and varied diet that contains plenty of fresh fruits and vegetables, whole grains, and moderate amounts of meats, poultry, and fish is good enough.

Adding herbs, supplements, or vitamins to the diet should be discussed with the doctor. As some supplements or herbs may interact or interfere with the effect of lupus medications. Herbs or supplements should never be used to replace medicines prescribed to control lupus symptoms or medication side effects.

Some items have to be eliminated from your diet because of the medications or the damage that lupus has done to specific body parts. Some diets may be altered or modified due to certain damages done to the body by lupus, such as kidney disease, liver damage, muscle pains, or more. Alcohol and meat consumption are always recommended to be in moderation if lupus has damaged your organs. 

PPARs and LUPUS

There is no cure for lupus. Yet, some medications, treatments, and therapies may help to alleviate the symptoms and flare-ups. According to studies, PPARs help to ease the symptoms and also suppress inflammation. It may also help in inhibiting the inflammatory mediators and reverses the organ damages. 

PPARγ, also known as PPAR gamma, plays the most crucial role in suppressing the inflammatory actions caused by lupus. PPAR gamma, which is rich in anti-atherogenic and anti-inflammatory properties, regulates inflammation and immunity. PPARγ regulates the inflammatory signal initiated by activation of CD40, with is essential in the implications of immunological mechanisms in underlying systemic lupus erythematosus. 

Reference: https://pubmed.ncbi.nlm.nih.gov/24456224/

In terms of immunity, PPAR gamma and its ligands are the most critical ones for the modulation of immune cells like monocytes, T cells, NK cells, and inflammatory reactions. Women with systemic lupus erythematosus exhibit a high prevalence of hypertension, endothelial dysfunction, and renal injury. There is a study done on peroxisome proliferator activator receptor β/δ (PPARβ/δ) agonist, ameliorates disease activity and cardiovascular complications in a female mouse model of lupus. The study concluded that pharmacological activation of PPARβ/δ reduced hypertension, endothelial dysfunction, and organ damage in severe lupus, which was associated with reduced plasma anti-double-stranded DNA autoantibodies and anti-inflammatory and antioxidant effects target tissues. The findings identify PPARβ/δ as a promising target for an alternative approach in treating systemic lupus erythematosus and its associated vascular damage.

Reference: https://www.ahajournals.org/doi/full/10.1161/hypertensionaha.116.08655

Besides, as mentioned earlier, one of the robust functions of PPARs is that it rejuvenates cells and supports the healing process of damaged body tissues. PPARs have also been studied with reverse tissue damaging properties. 

Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386118/

Apart from PPAR gamma, PPAR alpha is also known for its magnificent effects on organ functions. PPAR α activation has conferred additional benefits on endothelial function, kidney function, and anti-inflammation. PPAR α- activators, such as hypolipidemic drugs in fibric acid class, were proven to have therapeutic effects on metabolic syndrome and cardiovascular disease.  

Reference: https://www.hindawi.com/journals/ppar/2010/345098/

The study above focuses on signaling pathways, ligand selectivity, and physio-pathological roles of PPAR in kidney diseases and the therapeutic utility of PPAR modulators in the treatment of diabetes and inflammation-induced nephropathy. As severe, lupus may also lead to kidney necrosis or kidney failure. Knowing the importance of PPAR α is also essential in showing that PPARs help alleviates organ damage and aid in reversing the damage done to the kidney. 

Reference: 

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386118/
  2. https://pubmed.ncbi.nlm.nih.gov/30393147/
  3. https://pubmed.ncbi.nlm.nih.gov/24456224/
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327470/
  5. https://grantome.com/grant/NIH/R01-AR047451-03
  6. https://www.scirp.org/journal/paperinformation.aspx?paperid=76656

In conclusion, all the studies above show how PPARs can help in lupus diseases. The best way to get access to PPARs is by taking supplements which is rich in PPARs. As for Crypto PPARs, it has not only one but contains 3 PPARs which PPARs alpha, PPARs beta, and PPARs gamma. These PPARs have been studied in lupus management, treatment, therapy, organ damage, and healing as above. Thus, it potentially could be the best solution for lupus. 

As for Crypto PPARs, it has 100% natural with no added preservatives, binders, or any other ingredients. It is 100% Chlorella Sorokiniana W87-10. Thus, it won't interfere with lupus medications. Moreover, it is very high in chlorophyll content which benefits the lupus patients who have anemia diseases. Furthermore, it has a chlorella growth factor which is also beneficial in lupus as it aids in cell rejuvenation and cell healing faster and quicker. Thus, it also benefits in replacing the damaged tissues and organs more quickly. 

The disease of 1000 faces - Lupus

The disease of 1000  faces - Lupus
  • What is lupus?
  • The most common type of lupus.
  • Causes, what's autoimmune disease?
  • Symptoms of lupus.
  • Effects of lupus on other organs
  • Lupus flare

 

What is Lupus?

Lupus is an autoimmune disease in which the body's immune system attacks its cells, tissues, and organs. As for lupus, it is a long-term autoimmune disease that causes inflammation, swelling, and damage. Inflammation caused by lupus can affect many different body systems, including your joints, skin, kidney, blood cells, brain, heart, and lungs. Lupus is also referred to as "The disease of 1000 faces". 

The most common type of LUPUS

  • Systemic lupus erythematosus (SLE)

 

Systemic lupus erythematosus (SLE) is the most common type of lupus. It is a systemic condition and has impacts on the body.SLE is more severe than other types of lupus because it affects the body's organs and organs system. The symptoms can typically range from mild to severe. It causes inflammation in the joints, skins, lungs, kidney, heart, blood, or a combination of these.  SLE is an autoimmune disease in which the immune system attacks its tissues, causing widespread inflammation and tissue damage to affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. This condition typically goes through cycles. At times of remission, the person will have no symptoms. However, during a flare-up, the disease is active, and symptoms appear.

 

Causes of Lupus

The leading cause of lupus is an autoimmune disease. As an autoimmune disease, lupus occurs when our immune system attacks the healthy tissues in our body. 

It appears that people with an inherited predisposition for lupus may develop the disease when they come into contact with something in the environment that can trigger lupus. The cause of lupus in most cases, however, is unknown. Some potential triggers include:

  • Infections: Infection can initiate lupus or cause a relapse in some people. 
  • Medications: Lupus can also be triggered by certain medications such as blood pressure medications, anti-seizure medications, and antibiotics. Those who have drug-induced lupus usually get better when they stop taking the medication. 
  • Sunlight. Exposure to the sun may bring on lupus skin lesions or trigger an internal response in susceptible people. 

 

What is autoimmune disease?

The immune system protects the body and fights off antigens, such as viruses, bacteria, and germs. Autoimmune disease occurs when the body's natural defense system fails to differentiate between its cells and foreign cells. This causes the body to attack normal cells mistakenly. 

The immune system protects the body and fights off antigens, such as viruses, bacteria, and germs.

It does this by producing proteins called antibodies. White blood cells, or B lymphocytes, produce these antibodies.

When a person has an autoimmune condition, such as lupus, the immune system cannot differentiate between unwanted substances, antigens, and healthy tissue.

As a result, the immune system directs antibodies against both the healthy tissue and the antigens. This causes swelling, pain, and tissue damage.

The most common type of autoantibody that develops in people with lupus is an antinuclear antibody (ANA). The ANA reacts with parts of the cell's nucleus, the command center of the cell.

These autoantibodies circulate in the blood, but some of the body's cells have walls permeable enough to let some autoantibodies through.

The autoantibodies can then attack the DNA in the nucleus of these cells. This is why lupus affects some organs and not others.

Why does the immune system go wrong?

Several genetic factors probably influence the development of SLE.

Some genes in the body help the immune system to function. However, changes in these genes may stop the immune system from working correctly in people with SLE.

According to Genetics Home Reference, one possible theory relates to cell death, a natural process that occurs as the body renews its cells.

Some scientists believe that, due to genetic factors, the body does not get rid of cells that have died.

These dead cells that remain may release substances that cause the immune system to malfunction.

 

Symptoms of lupus.

The symptoms of lupus occur during the time of flare-ups. However, between flare-ups, people usually experience times of remission when there are few or no symptoms.

Lupus has a wide range of symptoms, including:

  • Pain or swelling in joints and muscles. 
  • Swollen glands or lymph nodes.
  • skin rashes
  • ulcer in mouth
  • loss of appetite and weight loss. 
  • chest pain upon deep breathing
  • fatigue
  • sensitivity to the sun
  • fever
  • headaches
  • chest pain upon deep breathing
  • unusual hair loss
  • pale or purple fingers or toes from cold or stress (Raynaud's phenomenon)
  • arthritis

Effects of lupus on other organs and body systems

Apart from the symptoms listed above, lupus also impacts other organs and body systems. 

  • Lungs: Some people develop pleuritis, an inflammation of the chest cavity lining that causes chest pain, particularly breathing. Pneumonia may also eventually develop.

  • Kidneys: Lupus nephritis occurs when lupus autoantibodies affect structures in your kidneys that filter out waste. This causes kidney inflammation and may lead to blood in the urine, protein in the urine, high blood pressure, impaired kidney function, or even kidney failure. Around 1 in 3 people with lupus will have kidney problems.

  • Central nervous system: Lupus can sometimes affect the brain or central nervous system. Symptoms include headaches, dizziness, depression, memory disturbances, vision problems, seizures, stroke, or changes in behavior.

  • Blood: Lupus can cause anemia, leukopenia (a decreased number of white blood cells), or thrombocytopenia (a decrease in platelets in the blood, which assist in clotting).
  • Blood vessels: Vasculitis, or inflammation of the blood vessels, can occur. This can affect circulation.

  • Heart: If inflammation affects the heart, it can result in myocarditis and endocarditis. It can also affect the membrane that surrounds the heart, causing pericarditis. It may result in chest pain or other symptoms as well. Endocarditis can damage the heart valves, causing the valve surface to thicken and develop, result in growths that can lead to heart murmurs. 

Other complications involving lupus

Lupus can also increase the risk of several health problems, such as infections, bone tissue death, and pregnancy complications. 

  1. Pregnancy complication: A woman with lupus usually has difficulty getting pregnant. They are at higher risk of pregnancy loss, preterm birth, and preeclampsia. 
  2. Infection: Infection becomes more likely because both lupus and its treatments weaken the immune system. Common infections include urinary tract infections, respiratory infections, yeast infections, salmonella, herpes, and shingles.
  3. Bone tissue death: This occurs when there is a low blood supply to a bone. Tiny breaks can develop in the bone. Eventually, the bone may collapse. It most commonly affects the hip joint.

 

Lupus flare

What are lupus flares?

When the symptoms get worse and make you sick, that's called a flare. Flare usually comes and goes. It may cause swelling and rashes at times and be gone after few days. Sometimes it also happens without any apparent symptoms. The flares range from mild to worst conditions - which requires medical conditions. 

 

Pic reference: https://www.verywellhealth.com/what-causes-lupus-2249817

Triggers for lupus flares

Common triggers for lupus flares include:

  • Stress
  • Fatigue
  • Being in the sun or exposure to fluorescent/halogen light. 
  • Injuries
  • Infection
  • Stopping medication/skip medication
  • Certain types of food and many more.

Even with medications, lupus flare may still occur due to other triggers. 

Next article: https://crypto.com.my/blogs/news/ppars-and-lupus